The accident occurred on January 18 morning on the Samara-Shymkent road.
At least 52 people have been killed in a fire that broke out on a bus in Kazakhstan's northwestern Aqtobe region, authorities say. Five people managed to escape the inferno with injuries and are now undergoing medical treatment.
Kazakhstan's emergency services ministry set up a hotline for victims' relatives.
It is not yet clear who was travelling on the bus or where they were from, according to Tass.
Authorities said the bus had begun its journey in Shymkent and was traveling to Russian Federation.
Ministry representative Imankulov did not confirm this however, telling AFP: 'It's too early to talk about the reasons for the fire'.
The Icarus bus was traveling from Uzbekistan to Russian Federation via Kazakhstan.
The five survivors suffered minor burns and "other traumas" according to emergency services.
Video footage from the scene showed the bus in flames and emitting heavy black smoke.
A photograph posted online from the site showed the bus completely burnt out.
In 2015, 16 people, including three children, died in Kazakhstan when a minibus collided with a van on April 20, 2015.