"The expectation down there on the Welsh team is huge, rugby is like a way of life down there, so like any away game you've got to try and start well".
"The best ball you can play off is forcing turnovers and if the opposition are going to play more, that means there are more opportunities for us to get turnovers".
This was Warren Gatland's 98th match in charge for Wales - equalling the record of a Six Nations coach in charge of one country.
Warren Gatland's preparations for the tournament were disrupted by a number of key players being ruled out with various fitness concerns, including the likes of Sam Warburton, Taulupe Faletau, Dan Lydiate, Jonathan Davies and Liam Williams. Class in the 13 channel and set up Halfpenny's try.
Commander Cary Phillips drives the side while lock Natalia John, flanker Beth Lewis, scrum-half Jade Knight and wing Hannah Bluck will make debuts.
The annual tournament, which has roots that date back more than a century, consists of 15 matches played in a round-robin format between six teams - England, France, Ireland, Italy, Scotland, and Wales.
Scotland dominated the near half-hour to halftime but lapsed into error after error: Dropped passes, knock ons, a penalty kick not finding touch, and the backs shuffling the ball sideways, easily contained by Wales.The interval did not provide a fresh start.
Leigh Halfpenny added the second try soon after Davies got his side off the mark and Scotland were 14-0 down at halftime.
They did not have to wait long, however, as Scotland were penalised for an illegal feed into the resulting scrum, allowing Wales to work it left and then back to the right for Halfpenny to crash over.
The men in blue nilled Wales in the second half in Edinburgh a year ago and it looked like they could suffer the same fate in Cardiff in the first period. The conversion made it a personal tally of 22 for Halfpenny in Wales' 27-0 lead.
Wales kept threatening: Replacement prop Wyn Jones was held up by Scotland's Huw Jones, and replacement flyhalf Gareth Anscombe dropped a try-scoring pass from Alun Wyn Jones.
It was a flawless afternoon for Wales but there was one man who was nervous in the stadium - defence coach Shaun Edwards.
The challenge for Scotland in the final 10 minutes was to both avoid the shutout and deny Wales a fourth try and a bonus point.
Scotland: S Hogg, T Seymour, C Harris (P Horne 54), H Jones, B McGuigan (S Maitland 54), F Russell, A Price (G Laidlaw 48), G Reid (J Bhatti 48-75), S McInally (S Lawson 69), J Welsh (M McCallum 64), B Toolis (G Gilchrist 54), J Gray, J Barclay (captain), H Watson, C du Preez (R Wilson 48).